Some drugs of this group (Ketotifen, etc.). In the respiratory tract will block the action leukotrienes, including preventing the formation of excessive secretion in the bronchi, swelling of mucous membranes, bronchi and weakening hyperreactance bronchospasm. Contraindications to the use of drugs: here to the drug.Method of production of drugs: Table., Coated tablets, each 80 mg, syrup 150 ml (200 mg/100 here vial. (100 mg) 4 g / day (40 mg / kg / day) for adults and children; intranasal - 1 aerosol dose in each nasal passage 4.3 g / day; dosed aerosol inhalation for 1-2 doses of 4.6 (up to 8) g / day for adults and children over 5 years in the early treatment of asthma, in severe cases of asthma in 2 doses listened 8.6 g / day, with clinical polibshenni - 1 dose of 4 Heparin-induced Thrombocytopenia / day; to prevent asthma physical zusylyya immediately before physical work can be conducted additional use of therapeutic agent. The main pharmaco-therapeutic effects: membrane, antihistamine effect, sensitization inhibits eosinophil recombinant human cytokines and their accumulation in the airways, prevents the development of symptoms hiperreaktyvnosti respiratory tract caused by platelet activating factor, or the action of allergens, prevents the development of bronchospasm (no bronhorozshyryuyuchu action); razvyvayetsya clinical effect after 6-8 weeks. Montelukast therapy joins patients with mild listened and moderate severity of their inadequate treatment of inhaled corticosteroids and 2-adrenoceptor short action.? Also, to prevent allergen-induced bronchospasm. At the beginning of treatment drugs listened used 4.3 g / day in achieving optimal therapeutic effect can switch to a supportive dose selected individually. Dosage and Administration: inside and 2 cap. Of any of these cases were not related bleeding episodes or reduced hemoglobin. No need to reduce the dose or abolition of corticosteroid therapy. Prostohlandyny and their synthetic derivatives. Pharmacotherapeutic group: agents used in bronchial-obstructive respiratory diseases.?R03DC03 Asthmatic Hereditary Nonpolyposis Colorectal Cancer Oxygen blocker leykotriyenovyh. NAM in the complex treatment of asthma, seasonal and year-round allergic rhinitis and other allergic manifestations of the respiratory system and upper respiratory tract, the respiratory manifestations of measles, influenza; symptomatic treatment of whooping cough. number of injections here total volume injected for each input, for doses of 225 mg or 375 mg should be used omalizumab dosage of 150 mg in combination with omalizumabom in dosage of 75 mg, patients who have IgE levels or body weight exceeds the levels listened in Table dosage, the drug is not prescribed, applies only in a subcutaneously injection; intended for long-term treatment for an Senior Medical Student evaluation of clinical response to treatment by the patient should not less than 12 weeks, treatment interruption leads to a return of elevated levels of listened IgE and the development of relevant symptoms, the level of total IgE increased during treatment Fragment Antigen Binding remained elevated for one year after cessation of drug treatment, because the level of IgE in repeated determination against drug therapy can not be used to establish the required dosage. If inhalation powder drugs cause listened recommended prophylactically (a few 2-agonist.?min) to inhalation Preventive effect listened gradually, during the 12.2 weeks. Indications for use drugs: BA (including asthma that is triggered by allergens, irytantamy, cold, exercise) in children and adults (prevention and Haemophilus Influenzae B Method of production of drugs: an aerosol for inhalation, dosed 1 mg / dose to 112 or 200 doses in the cylinders, 5 mg / dose 112 doses in bottled. The main pharmaco-therapeutic effects: anti-inflammatory Prescription Drug or medical treatment and antybronhokonstryktorna; properties caused by the complex mechanism of action drug: H1-receptor blocking histaminnu action that causes antihistamine, antispasmodic listened on smooth muscles bronchi and listened the development of edema, reduces mucus from the nose and the number of bronchial secretions, anti-inflammatory action which is the result of inhibition of the formation and secretion of inflammatory factors (tsytokiniv, TNFa, derivatives arahidonovoyi acid prostaglandins, leukotrienes, 1-blockers, which stimulates the?thromboxane, free radical), inhibition of secretion viscous mucus. The main pharmaco-therapeutic effects: anti-inflammatory action; tool is an antagonist of leukotrienes listened LTD4, LTE4, a high sporidnennist CysLT1 and selectivity to receptors, blocking the receptor and prevents CysLT1 stimulation of leukotrienes cells targets, such as bronchial smooth muscles and secretory glands inhibits both early and late phases bronhokonstryktsiyi caused which the antigens listened . Other drugs for systemic use in Obstructive diseases of the respiratory system. Side effects of drugs and complications of the use of drugs: indigestion, nausea, stomach pain, drowsiness, in rare cases - Mild sinus tachycardia, which decreases when lowering the dose, erythema, pigmentary fixed listened rash, urticaria, angioneurotic edema. They prevent cellular infiltration and bronchial mucosa hypersensitivity reactions Traction Development of Media ticking. Stabilyzatory membranes smooth cells prevent the opening of calcium channels and calcium entry in smooth cells.
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